Hypoglycemic Effects of Stereospermum Personatum, Senna Obtusifolia, and Amomum Subulatum Extracts in a Swiss Albino Mice Model

EasyChair Preprint 14989

Abstract

The prevalence of diabetes continues to rise globally, leading to increased interest in alternative and herbal treatments with fewer side effects. This study investigates the hypoglycemic effects of Stereospermum personatum, Senna obtusifolia, and Amomum subulatum extracts in a Swiss albino mice model. A total of 30 Swiss albino mice were divided into five groups: a control group, a diabetic-induced group, and three treatment groups receiving different plant extracts. Diabetes was induced using alloxan, followed by oral administration of the plant extracts over a period of four weeks. Blood glucose levels were measured at regular intervals, and the results were compared to those of the control group. The extracts showed significant hypoglycemic activity, with Amomum subulatum demonstrating the most pronounced effect, followed by Stereospermum personatum and Senna obtusifolia. Histopathological analyses of pancreatic tissues revealed regenerative effects in the treatment groups. These findings suggest that these plant extracts possess potential antidiabetic properties, making them viable candidates for further exploration in diabetes management.

Keyphrases: Albino, Amomum, Diabetes, Hypoglycemia, Senna, Stereospermum, Swiss, extracts, herbal, mice, obtusifolia, personatum, subulatum

@booklet{EasyChair:14989,
  author    = {Joshua Cena},
  title     = {Hypoglycemic Effects of Stereospermum Personatum, Senna Obtusifolia, and Amomum Subulatum Extracts in a Swiss Albino Mice Model},
  howpublished = {EasyChair Preprint 14989},
  year      = {EasyChair, 2024}}